The sqlite3 module allows Python to interact with SQLite databases. It can connect to a database, execute SQL statements like CREATE, INSERT, UPDATE and DELETE, and fetch the results. The cursor object is used to execute SQL and manage results. Connecting to the database returns a Connection object, and calling cursor() on that returns a Cursor object used to execute statements and queries. Changes are committed using conn.commit() and resources are closed with cursor.close() and conn.close().