This document presents a new method for estimating motion in flotation froth images using mutual information as the similarity metric. It proposes using mutual information with a bin size of two (MI2) for block matching motion estimation of froth images. The paper finds that MI2 improves motion estimation accuracy in terms of peak signal-to-noise ratio compared to the commonly used mean absolute difference (MAD) metric, while having a similar computational cost. It tests the MI2 method on two froth video sequences using three-step search and new three-step search, and finds MI2 yields slightly better reconstructed image quality than MAD according to PSNR measurements.