This document describes the objectives and activities of Work Package 3 (WP3) of the SaferBrain project, which aims to develop innovative guidelines and tools to improve safety for vulnerable road users (VRUs) in Brazil and India. WP3 focuses on defining safety measures and methodologies, developing a GIS-based decision support system (DSS) to identify suitable safety strategies, and programming the DSS software. The DSS is intended to support experts in analyzing VRU accidents, identifying critical safety issues, estimating the benefits of safety countermeasures, and conducting road safety audits and inspections. It incorporates international best practices and research to provide a customized methodology for assessing VRU safety in Brazil and India.