Mendine Pharmaceuticals, established in 1937, has evolved from a sole proprietorship to a private limited company, now with multiple branches in India. The company focuses on optimizing its supply chain through strategic logistics activities, including inbound, outbound, and reverse logistics, while establishing reorder levels based on statistical sales analysis. The study aims to develop a feasible route coverage plan and optimize inventory levels to improve responsiveness and reduce costs in the distribution routes of East Midnapur and surrounding areas.