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Visualization of life science research by using MeSH and GIS techniques (summrized English verstion)
- 1. Visualization of life science research by using MeSH and GIS techniques Masashi Shirabe
- 2. This work is done as a part of the project “Scientometrics conducive to management of funding programs”, which supported by JST/RISTEX.e of funding programs
- 3. Summary • By using MeSH, academic papers in life science field have been mapped. – Research topics are mapped in reasonable positions. – Research topics and fields on the maps can be interpreted even by non-specialists – Micro, meso, and macro maps are available. • By using GIS techniques, some information can be overlaid on such maps. As its result, quality and quantity indicators as well as categories are visualized. • Please give your comments on… – How could you use these maps in your operations? – How can we improve the maps? – What type of indicators should be overlaid on the maps?
- 4. On data • academic papers – intersection of the following two datasets • articles, reviews, notes, letters, and article & proceedings papers in WoS（SCI Ex） – DBYs are 1992-2011 • records on PubMed database – Publication years are 1991-2012 – Top m% cited papers are identified by our original program • patent data – utility patents registered to USPTO between 1992-2012. – paper citations (i.e., science linkages) are identified by our original program (http://link.springer.com/article/10.1007%2Fs11192-014-1293-8).
- 5. A result of mapping life science research (macro map)
- 6. A result of mapping life science research (macro map) nursing, health care psychiatric medicine, behavioral science neuroscience diagnosis, treatment metabolism, biochemistry molecular biologyenzyme, protein disease germ, virus, infectionimmunology stem cell pharmacology pathology plant science drug, physiology related science environment, ecology materials public health sequence homogeneity unclear regions analytical chemistry
- 7. Change of number of papers published in the world (2000-11) 量 Increase rapidly in all the fields世
- 8. Intertemporal Comparison ２０００ (moving average) ２０１０ (MA) 量 psychiatric medicine, behavioral science, physiology / diagnosis technology, system biology, analytical chemistry … UP 世
- 9. Change of number of papers published in Japan (2000-11) 量 stagnation (unchanged)日
- 10. Intertemporal Comparison ２０００ (MA) 2010 (MA) 量 sequence homogeneity … DOWN physiology / diagnosis technology, system biology, stem cell research … UP 日
- 11. Change of shares of Japanese papers (2000-10) 比 率 general declines日
- 12. Intertemporal Comparison ２０００ (MA) ２０１０ (MA) 比 率 日
- 13. Change of relative numbers of papers cited by US patents Registered between 2001 and 11 量 Basic research papers are highly cited世
- 14. Intertemporal Comparison 2001 2011 量 diagnosis technology, theoretical model … UP sequence homogeneity … DOWN 世
- 15. Change of share(Japanese papers cited by patents / all paper cited by patents) Registered between 2001 and 11 質 Shares are increasing (legacy of the past) 日
- 16. Intertemporal Comparison 2001 (MA) ２０11 (MA) 質 日
- 17. Change of share (patent citations of Japanese papers / that of the world) Registered between 2001 and 11 比 率 日
- 18. Intertemporal Comparison 2001 (MA) 2011 (MA 比 率 日
- 19. Implications • In life science – Number of papers in the world has steadily increased. – Although Japanese shares in most field were over 10% around 2000, they has declined just over 6 %. – In terms of citations by patents, physiology, diagnosis technology, system biology gained attentions recently. – Both citations and number of cited papers in Japan increased recently. (legacy of the past)
- 20. What we have done: Developed research platform • Database combined SCI Ex and PubMed Pubmed SCI Ex （WoS） linked MeSH • structured • relatively easy to interpret Funding info. citation -> evaluation acknowledge ment affiliation-> international, sector, institutional analysis USPTO IPC,PCT-> tech field… cite From 12 million PubMed records, 8.5 million records are linked to SCI Ex records.
- 21. Scope of our project biblio info (SCI, US patents, PubMed) Macro/micro map NIH funding evaluation by citation info and visualization of citation evaluation of contribution to innovation (science linkage analysis) evaluation of funding programs by acknowledge Networking triggered by NIH funding programs Overall visualization
- 22. Scope of our project biblio info (SCI, US patents, PubMed) Macro/micro map NIH funding evaluation by citation info and visualization of citation evaluation of contribution to innovation (science linkage analysis) evaluation of funding programs by acknowledge Networking triggered by NIH funding prgorams Overall visualization Presented in this file macro: life science micro: pluripotent stem cell research
- 23. ライフサイエンス other visualizations of life science research
- 24. Mapping by the second level descriptors Easy to interpret, luck of detail information
- 25. mapping by second level descriptor X qualifier perfectly understandable, but retandatnt
- 26. It remains unanswered which mapping methods are better in application.
- 27. Distribution of life science paper in the world 量 世
- 28. Distribution of Japanese life science papers 量 Weak in left hand side (clinical medicine and related fields) 日
- 30. number of Japanese Top 1% cited papers 量 Basic research!日
- 31. Japanese share in Top 1% cited papers 世界平均 質 日
- 32. Japanese share in Top 10% cited papers 世界平均 質 日
- 33. Average citations by US patents (per paper) 質 basic research papers are cited世
- 34. Japanese share in papers cited by US patent 世界平均 質 日
- 35. Japanese share of citations by US patents 世界平均 質 日
- 36. Implications • Basic research papers are more published in the world. • In comparison to the world, Japan has been focused on basic research. – This phenomena are partially explained by the fact that clinical papers, especially case report papers by Japanese physicians are likely to be published in Japanese journal. • Basic research papers are more cited by US patents. • Japanese papers in health care and drug, biochemistry are relatively cited. • Ration of top 1% / 10% cited Japanese papers to all Japanese papers are lower than its world average.
- 37. Japanese papers with public funding (2010) 量 Protein!日
- 38. Breakdown (2010) Grants-in-aid MHLW Grants 量 日
- 39. Breakdown (2010) JST NEDO (of METI) 量 日
- 40. Share of publically funded papers (2010) 比 率 日
- 41. Share of papers funded by Grants-in-aid 比 率 日
- 42. Share of papers funded by MHLW Grants 比 率 日
- 43. Shares of papers funded by JST 比 率 日
- 44. Share of papers funded by NEDO 比 率 日
- 45. Share of Grants-in-aid – Share of MHLW Grants 比 較 日
- 46. Implications • In terms of quantity, public research funds are contributing to paper productions in basic research. – In terms of research quality… • Each funding agency has its specific funding pattern, which fits its role. • However, judging from output indicators, public supports to clinical research and disease research seem insufficient. – Who pays currently？ Private companies?
- 47. Pluripotent stem cell research
- 48. Mapping of Pluripotent stem cell research
- 49. Mapping of Pluripotent stem cell research ES cells iPS cell tissue eng. mesenchymal SC culture regenerative mdeicineembryo research nerve embryonic carcinoma cell osteoplastic cell gene transfection Experimental Animals RT-PCRbase sequence unclear areas pluripotent SC
- 50. Number of Pluripotent stem cell research papers in the world 量 世
- 51. Change of number of Pluripotent stem cell research papers in the world (2000-10) 量 世 2000-2010（3年移動平均）
- 52. Change of number of Pluripotent stem cell research papers cited by US patent absolute number relative number 量 世 2001-2011年登録特許（3年移動平均）
- 53. Japanese share of Pluripotent stem cell research papers 比 率 高い世界シェア日
- 54. Change of Japanese share of Pluripotent stem cell research papers 比 率 2005年以前は論文数が少なく ノイズが多い。 日 2000-2010（3年移動平均）
- 56. Japanese share of top 1 % cited papers 世界平均 質 In ES and iPS research, the shares are similar to world averages.日
- 57. Japanese share of top 10 % cited papers 世界平均 質 日
- 58. Japanese Share of papers cited by US patents Attention to legend -> 質 日
- 59. Change of papers cited by patents by registered years 質 日 2001-2011 (MA)
- 60. Pluripotent stem cell research papers funded publically in Japan 量 日
- 61. Share of pluripotent stem cell research papers funded publically in Japan to all Japanse pluripotent stem cell research papers 貢 献 日
- 62. Funded by Grants-in-aid number share 比 率 量 日 日
- 63. JST number share 比 率 量 日 日
- 64. MHLW Grants number share 比 率 量 日 日
- 65. NEDO (of METI) number share funded projects are identified 比 率 量 日 日
- 66. Future research • Technical problems – mapping parameter – improve two dimensional expression • Overlaid information – funding information • money.. – funded institution – science linkages may show different patters by IPCs… – Comparisons to NIH funding • meso level mapping – mapping by the 4th or 5th level descriptors • more detailed micro maps (for supporting researchers’ activity) • Cope with (real and potential) users’ request
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