This document discusses best practices for designing natural user interfaces. It begins by defining natural interfaces as those that mimic natural human communication through gestures, expressions, and physical manipulation. The document then outlines guidelines for interface design, including making interfaces intuitive through realism and reducing cognitive load. It also describes a three-stage design process involving paper mockups, previsualizations, and interactive prototypes. Emerging technologies like Microsoft Surface and Apple's iPad/iPhone are examined. Open research questions on gestures, hand dominance, and other factors are presented.