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WHAT THE IOT SHOULD LEARN
FROM THE LIFE SCIENCES
BE OPEN OR MISS OUT!
or
http://knowledge.openboxsoftware.com/blog/
the-evolution-of-business-intelligence
excerpt from
modified, image from http://www.householdappliancesworld.com
health
management
air conditioning
smart heating
communications
security
entertainment
lighting controlweather
monitoring
room occupancy
Internet
mobile devices
“everything else”
‣ Everything is connected
‣ Big, noisy, often
unstructured data
www.thingslearn.com
Analytics, context integration, machine learning
and predictive modelling for the IoT.
0 clean shirt left
+
washing machine estimates
97% of your last pack of
powder used
+
it’s Wednesday, 23:55
+
the last four Thursdays
had a morning business
meeting
+
the car is parked 20 m from
a shop
+
last retail activity: 8 sec ago
Send immediate text
reminder to pick up
washing powder + send
tweet from @BorisHouse
“need identified” AND
“notification appropriate”Actionable insight.
From everything.
health
management
air conditioning
smart heating
communications
security
entertainment
lighting controlweather
monitoring
room occupancy
everything is an app! no interfaces!
from https://hello.is
THE CONSUMER IOT FAILS FOR
ITS LACK OF CONNECTEDNESS
Matt Hatton, Machina Research
The BLN IoT ‘14
Internet replaces wire
It’s all about the
connectedness
M2M
consumer
IoT
• Computational biologist
• Research group leader
• Lecturer in genome biology
• Advisor at
Who is
@BorisAdryan
was
EXPECTATION MANAGEMENT
DNA = storage of a blueprint
RNA = ‘active copy’ of DNA
protein = the building blocks
of cells and tissues
LIFE AS WE KNOW IT
transcription
translation
Gregor Johann Mendel,
exhibited in the Library at the NIMR
• Reading DNA information
• Determining “the sequence
of a gene” was a PhD in the
early 1980s
• Data processing was mainly
transcribing the observation
into a research paper
BIOLOGY THEN AND NOW
SEQUENCE INFORMATION
Sanger sequencing
ca. 1980
http://www.eplantscience.com
BIOLOGY THEN AND NOW
SEQUENCE INFORMATION
BIOLOGY THEN AND NOW
GENE ACTIVITY INFORMATION
2
6 ATP
• Signal transduction and
metabolic pathways
• Characterisation of proteins
and substrates that mediate
chemical reactions
• Nobel prize material
BIOLOGY THEN AND NOW
BIOCHEMISTRY
• We know about 250k
metabolites
• 100k protein structures
• on the order of 10k
different chemical
reactions
BIOLOGY THEN AND NOW
BIOCHEMISTRY
‣ Everything is connected
‣ Big, noisy, often
unstructured data
‣ We had studied how
biological entities depend
on each other
LIFE SCIENCE STRATEGIES
DON’T WORK IN THE IOT
- There are no commonly accepted
- ‘catalogue’ of things,
- ‘ontology’ of things,
- ‘data format’ of things,
- ‘meta data’ for things.
- Most businesses are driven by revenue, not
long-term strategic vision
- Service providers have no need to publish
- Data can be highly personal (cheap excuse)
unless they’re
WE HAVE A PROBLEM WITH
KNOWLEDGE REPRESENTATION
FORMALISING KNOWLEDGE
FORMALISING KNOWLEDGE
WITH GENE ONTOLOGY
CURRENT GOVERNMENT
INVESTMENTS INTO GENE
ONTOLOGY
NIH alone spent $44,616,906 on the
ontology structure since 2001
(no data for UK/EU spendings)
~100 full-time salaries for experts with
domain-specific knowledge
~40,000 terms
Oct. 1995
TOWARDS MIAMI AND
DATA REPOSITORIES
cf. IoT
Nov. 1993
META DATA, SHARING AND
DATA REPOSITORIES
founded in Nov. 1999
But this is a complex and ambitious project, and is one of the biggest challenges that
bioinformatics has yet faced. Major difficulties stem from the detail required to describe the
conditions of an experiment, and the relative and imprecise nature of measurements of
expression levels.The potentially huge volume of data only adds to these difficulties.
Nature
Feb. 2000
“
“
Nov. 2000
Oct. 2002
Wide adoption as
requirement for
publication in
scientific journals
META DATA, SHARING AND
DATA REPOSITORIES
cf. IoT 2015
since 2003
Semantic Sensor Network Ontologyhttp://en.wikipedia.org/wiki/Silo
Boris IoT slides
story
measurements
+ meta data
open, public repositories
human
curators
ontology
terms
community
PUBLISH OR PERISH
ok?
journal
informal exchange - no credit!
funders
assessment
The majority of this
infrastructure is paid for by
governments and charities
industry!
Boris IoT slides
measurements
+ meta data
storage &
provenance
human
curators
ontology
terms
user
PUBLISH OR YOU’RE NOT DOING IOT
ok?
Maybe the majority of this
infrastructure should be
paid for by governments?
company
cloud
device
registration
“ “
privileges
dataadded
value
0 clean shirt left
+
washing machine estimates
97% of your last pack of
powder used
+
it’s Wednesday, 23:55
+
the last four Thursdays
had a morning business
meeting
+
the car is parked 20 m from
a shop
+
last retail activity: 8 sec ago
Send immediate text
reminder to pick up
washing powder + send
tweet from @BorisHouse
“need identified” AND
“notification appropriate”Actionable insight.
From everything.
“indicator of esteem”
3% left and
not pressed
“not home”
“buying”
credit card:
“highly personal device”
~ alive and awake
SECURITY AND PRIVACY
http://iot.ghost.io
THE INTERNET OF SUB-NETS?
https://www.smartthings.com
https://flic.io/partners
Dr. Boris Adryan
@BorisAdryan
@thingslearn
@SoftwareSaved
Open software
Open source
Open data
Fellow of the
Check out my talk on ‘Ontologies in the IoT’ on SlideShare:
http://www.slideshare.net/BorisAdryan

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Boris IoT slides

  • 1. WHAT THE IOT SHOULD LEARN FROM THE LIFE SCIENCES BE OPEN OR MISS OUT! or
  • 3. modified, image from http://www.householdappliancesworld.com health management air conditioning smart heating communications security entertainment lighting controlweather monitoring room occupancy
  • 5. ‣ Everything is connected ‣ Big, noisy, often unstructured data www.thingslearn.com Analytics, context integration, machine learning and predictive modelling for the IoT.
  • 6. 0 clean shirt left + washing machine estimates 97% of your last pack of powder used + it’s Wednesday, 23:55 + the last four Thursdays had a morning business meeting + the car is parked 20 m from a shop + last retail activity: 8 sec ago Send immediate text reminder to pick up washing powder + send tweet from @BorisHouse “need identified” AND “notification appropriate”Actionable insight. From everything.
  • 7. health management air conditioning smart heating communications security entertainment lighting controlweather monitoring room occupancy everything is an app! no interfaces!
  • 9. THE CONSUMER IOT FAILS FOR ITS LACK OF CONNECTEDNESS Matt Hatton, Machina Research The BLN IoT ‘14 Internet replaces wire It’s all about the connectedness M2M consumer IoT
  • 10. • Computational biologist • Research group leader • Lecturer in genome biology • Advisor at Who is @BorisAdryan was EXPECTATION MANAGEMENT
  • 11. DNA = storage of a blueprint RNA = ‘active copy’ of DNA protein = the building blocks of cells and tissues LIFE AS WE KNOW IT transcription translation Gregor Johann Mendel, exhibited in the Library at the NIMR
  • 12. • Reading DNA information • Determining “the sequence of a gene” was a PhD in the early 1980s • Data processing was mainly transcribing the observation into a research paper BIOLOGY THEN AND NOW SEQUENCE INFORMATION Sanger sequencing ca. 1980 http://www.eplantscience.com
  • 13. BIOLOGY THEN AND NOW SEQUENCE INFORMATION
  • 14. BIOLOGY THEN AND NOW GENE ACTIVITY INFORMATION
  • 15. 2 6 ATP • Signal transduction and metabolic pathways • Characterisation of proteins and substrates that mediate chemical reactions • Nobel prize material BIOLOGY THEN AND NOW BIOCHEMISTRY
  • 16. • We know about 250k metabolites • 100k protein structures • on the order of 10k different chemical reactions BIOLOGY THEN AND NOW BIOCHEMISTRY
  • 17. ‣ Everything is connected ‣ Big, noisy, often unstructured data ‣ We had studied how biological entities depend on each other
  • 18. LIFE SCIENCE STRATEGIES DON’T WORK IN THE IOT - There are no commonly accepted - ‘catalogue’ of things, - ‘ontology’ of things, - ‘data format’ of things, - ‘meta data’ for things. - Most businesses are driven by revenue, not long-term strategic vision - Service providers have no need to publish - Data can be highly personal (cheap excuse) unless they’re
  • 19. WE HAVE A PROBLEM WITH KNOWLEDGE REPRESENTATION
  • 22. CURRENT GOVERNMENT INVESTMENTS INTO GENE ONTOLOGY NIH alone spent $44,616,906 on the ontology structure since 2001 (no data for UK/EU spendings) ~100 full-time salaries for experts with domain-specific knowledge ~40,000 terms
  • 23. Oct. 1995 TOWARDS MIAMI AND DATA REPOSITORIES cf. IoT Nov. 1993
  • 24. META DATA, SHARING AND DATA REPOSITORIES founded in Nov. 1999 But this is a complex and ambitious project, and is one of the biggest challenges that bioinformatics has yet faced. Major difficulties stem from the detail required to describe the conditions of an experiment, and the relative and imprecise nature of measurements of expression levels.The potentially huge volume of data only adds to these difficulties. Nature Feb. 2000 “ “ Nov. 2000 Oct. 2002 Wide adoption as requirement for publication in scientific journals
  • 25. META DATA, SHARING AND DATA REPOSITORIES cf. IoT 2015 since 2003 Semantic Sensor Network Ontologyhttp://en.wikipedia.org/wiki/Silo
  • 27. story measurements + meta data open, public repositories human curators ontology terms community PUBLISH OR PERISH ok? journal informal exchange - no credit! funders assessment The majority of this infrastructure is paid for by governments and charities industry!
  • 29. measurements + meta data storage & provenance human curators ontology terms user PUBLISH OR YOU’RE NOT DOING IOT ok? Maybe the majority of this infrastructure should be paid for by governments? company cloud device registration “ “ privileges dataadded value
  • 30. 0 clean shirt left + washing machine estimates 97% of your last pack of powder used + it’s Wednesday, 23:55 + the last four Thursdays had a morning business meeting + the car is parked 20 m from a shop + last retail activity: 8 sec ago Send immediate text reminder to pick up washing powder + send tweet from @BorisHouse “need identified” AND “notification appropriate”Actionable insight. From everything. “indicator of esteem” 3% left and not pressed “not home” “buying” credit card: “highly personal device” ~ alive and awake
  • 32. THE INTERNET OF SUB-NETS? https://www.smartthings.com https://flic.io/partners
  • 33. Dr. Boris Adryan @BorisAdryan @thingslearn @SoftwareSaved Open software Open source Open data Fellow of the Check out my talk on ‘Ontologies in the IoT’ on SlideShare: http://www.slideshare.net/BorisAdryan