This document discusses how to incorporate hypothesis generation and testing (Design Question 4) into elementary science classrooms. It provides examples of how to do this in ecology/life science, physical science, and space science lessons. For ecology, students would predict how to sort species cards and then compare to the scientific method. For physical science, students would hypothesize how to make a sound-making instrument and test their predictions. For space science, students would model and predict the causes of seasons. The document advises that teachers can adapt existing lab activities by having students first make predictions and then reflect on results. The goal is for students to use the scientific process of predicting, testing, and reflecting.