The 10th International Conference on Software and Computer Applications (ICSCA 2021) will be held virtually from February 23-26, 2021 due to the COVID-19 pandemic. The conference aims to provide a platform for academics, researchers, students, and professionals to present research in software and computer applications. This year marks the first time the conference will be conducted online. The conference schedule includes keynote speeches, paper presentations, and networking opportunities. Topics will include computer theory, software design, data mining, image analysis, and more. The organizing committee hopes participants can still exchange ideas and network despite the virtual format due to the pandemic.