The document discusses challenges and advancements in serial link interfaces, with a focus on the next-generation SERDES systems aimed at increasing data rates, particularly from NRZ to PAM-4 modulation. It outlines trends in wireline communications, including the demand for enhanced equalization and the need for cost-effective solutions like multi-mode fibers. Additionally, it reviews research outcomes from the Analog Integrated Circuits Lab at the University of Pavia, highlighting various approaches for improving data transmission efficiency and reducing power consumption.