This document outlines strategies for differentiating instruction to meet the needs of high-ability learners. It discusses assessing students' readiness, interests, and learning profiles through pre-assessments. Differentiation strategies presented include tiered activities, learning centers, compacting, independent projects, acceleration, and mentorships. The document emphasizes starting small with differentiation and giving students choices that appeal to their varying skills, interests, and preferences. The goal of differentiation is to customize instruction so all students continuously learn.