This document analyzes the seismic performance of multi-storey reinforced concrete buildings with and without mass irregularity using the ETABS software. Five building models are considered - four with different mass irregularity configurations by varying the slab thickness, and one regular building. The models are analyzed for parameters like storey displacements, drifts, and shear. Results show displacements and drifts are highest in models with mass irregularity compared to the regular model. Shear is also highest in the irregular models, with the maximum values in the model with increased slab thickness in the bottom five storeys. In conclusion, the presence of mass irregularity deteriorates the seismic performance of buildings.